Protocol for the PreventIT feasibility randomised controlled trial of a lifestyle-integrated exercise intervention in young older adults

Authors: Kristin Taraldsen1, A Stefanie Mikolaizak, Andrea B Maier, Elisabeth Boulton, Kamiar Aminian, Jeanine van Ancum, Stefania Bandinelli, Clemens Becker, Ronny Bergquist, Lorenzo Chiari, Lindy Clemson, David P French, Brenda Gannon, Helen Hawley-Hague, Nini H Jonkman, Sabato Mellone, Anisoara Paraschiv-Ionescu,   Mirjam Pijnappels, Michael Schwenk, Chris Todd, Fan Bella Yang, Anna Zacchi, Jorunn L Helbostad,Beatrix Vereijken Abstract Introduction The European population is rapidly ageing. In order to handle substantial future challenges in the healthcare system, we need to shift focus from treatment towards health promotion. The PreventIT project has adapted the Lifestyle-integrated Exercise (LiFE) programme and developed an intervention for healthy young older adults at risk of accelerated functional decline. The intervention targets balance, muscle strength and physical activity, and is delivered eitherRead More

Muscle mass and muscle strength are associated with pre- and post-hospitalization falls in older male inpatients: a longitudinal cohort study

Authors: Van Ancum JM, Pijnappels M, Jonkman NH, Scheerman K, Verlaan S, Meskers CGM, Maier AB. Abstract BACKGROUND: Low muscle mass and strength are highly prevalent in inpatients. It is acknowledged that low muscle mass and strength are associated with falls in community-dwelling older adults, but it is unknown if these muscle measures are also associated with falls in a population of older inpatients. This study aimed to investigate the association between muscle measures and pre- and post-hospitalization falls in older inpatients. METHODS: An inception cohort of patients aged 70 years and older, admitted to an academic teaching hospital, was included inRead More

Is being malnourished according to the ESPEN definition for malnutrition associated with clinically relevant outcome measures in geriatric outpatients?

Authors: van Rijssen NM, Rojer AGM, Trappenburg MC, Reijnierse EM, Meskers CGM, Maier AB, de van der Schueren MAE. Abstract BACKGROUND AND AIM: A body of evidence is supporting the association between (the risk of) malnutrition in relation to physical performance, muscle strength, risk for depression and cognitive status in geriatric outpatients. Associations between being malnourished according to the newly proposed ESPEN definition for malnutrition and clinically relevant outcome measures of the aforementioned variables have not been confirmed yet. Therefore, the aim of this study was to examine the association between being malnourished according to the ESPEN definition and clinically relevantRead More

Feasibility and Effectiveness of Intervention Programmes Integrating Functional Exercise into Daily Life of Older Adults: A Systematic Review

Authors: Weber M, Belala N, Clemson L, Boulton E, Hawley-Hague H, Becker C, Schwenk M. Abstract BACKGROUND: Traditionally, exercise programmes for improving functional performance and reducing falls are organised as structured sessions. An alternative approach of integrating functional exercises into everyday tasks has emerged in recent years. OBJECTIVES: Summarising the current evidence for the feasibility and effectiveness of interventions integrating functional exercise into daily life. METHODS: A systematic literature search was conducted including articles based on the following criteria: (1) individuals ≥60 years; (2) intervention studies of randomised controlled trials (RCTs) and non-randomised studies (NRS); (3) using a lifestyle-integrated approach;Read More

Knee extension strength measurements should be considered as part of the comprehensive geriatric assessment

Authors: Suey S. Y. Yeung, Esmee M. Reijnierse, Marijke C. Trappenburg, Gerard J. Blauw, Carel G. M. Meskers & Andrea B. Maier Background Comprehensive geriatric assessment (CGA) generally includes handgrip strength (HGS) as a measure of overall muscle strength that is associated with various health characteristics in geriatric outpatients. Whether this is also true for knee extension strength (KES) is yet unknown. This study aims to compare the associations between health characteristics from the CGA with both HGS and KES in geriatric outpatients. Methods Data were retrieved from a cross-sectional study. A total of 163 community-dwelling older adults referred to a geriatric outpatient clinic of aRead More

Lack of knowledge and availability of diagnostic equipment could hinder the diagnosis of sarcopenia and its management

Authors: Reijnierse EM, de van der Schueren MAE, Trappenburg MC, Doves M, Meskers CGM, Maier AB. Abstract OBJECTIVES: Sarcopenia is an emerging clinical challenge in an ageing population and is associated with serious negative health outcomes. This study aimed to assess the current state of the art regarding the knowledge about the concept of sarcopenia and practice of the diagnostic strategy and management of sarcopenia in a cohort of Dutch healthcare professionals (physicians, physiotherapists, dietitians and others) attending a lecture cycle on sarcopenia. MATERIAL AND METHODS: This longitudinal study included Dutch healthcare professionals (n = 223) who were asked to completeRead More

Assessment of maximal handgrip strength: how many attempts are needed?

Authors:Reijnierse EM, de Jong N, Trappenburg MC, Blauw GJ, Butler-Browne G, Gapeyeva H, Hogrel JY, McPhee JS, Narici MV, Sipilä S, Stenroth L, van Lummel RC, Pijnappels M, Meskers CGM, Maier AB. Abstract BACKGROUND: Handgrip strength (HGS) is used to identify individuals with low muscle strength (dynapenia). The influence of the number of attempts on maximal HGS is not yet known and may differ depending on age and health status. This study aimed to assess how many attempts of HGS are required to obtain maximal HGS. METHODS: Three cohorts (939 individuals) differing in age and health status were included. HGSRead More

eHealth interventions to promote objectively measured physical activity in community-dwelling older people

Authors:Jonkman NH, van Schooten KS, Maier AB, Pijnappels M. Abstract eHealth solutions are increasingly being applied to deliver interventions for promoting an active lifestyle in the general population but also in older people. Objective assessment of daily physical activity (PA) is essential to accurately and reliably evaluate the effectiveness of such interventions. This review presents an overview of eHealth interventions that focus on promoting PA in community-dwelling older people, and discusses the methods used to objectively assess PA, and the effectiveness of the eHealth interventions in increasing PA. The twelve eHealth intervention studies that met our inclusion criteria used aRead More

Predicting Trajectories of Functional Decline in 60- to 70-Year-Old People

AUTHORS: Jonkman NH, Del Panta V, Hoekstra T, Colpo M, van Schoor NM, Bandinelli S, Cattelani L, Helbostad JL, Vereijken B, Pijnappels M, Maier AB. Abstract BACKGROUND: Early identification of people at risk of functional decline is essential for delivering targeted preventive interventions. OBJECTIVE: The aim of this study is to identify and predict trajectories of functional decline over 9 years in males and females aged 60-70 years. METHODS: We included 403 community-dwelling participants from the InCHIANTI study and 395 from the LASA study aged 60-70 years at baseline, of whom the majority reported no functional decline at baseline (medianRead More

German version of the Community Balance and Mobility Scale

Authors: Katharina Gordt, A. Stefanie Mikolaizak, Corinna Nerz, Carolin Barz, Thomas Gerhardy, Michaela Weber, Clemens Becker, Michael Schwenk Abstract Background Tools to detect subtle balance deficits in high-functioning community-dwelling older adults are lacking. The Community Balance and Mobility Scale (CBM) is a valuable tool to measure balance deficits in this group; however, it is not yet available in the German language. Objective The aim was 1) to translate and cross-culturally adapt the CBM into the German language and 2) to investigate the measurement properties of the German CBM (G-CBM). Material and methods The original CBM was translated into the German language according toRead More

Comparison of Standard Clinical and Instrumented Physical Performance Tests in Discriminating Functional Status of High-Functioning People Aged 61⁻70 Years Old

Authors: Alice Coni, Jeanine M. van Ancum, Ronny Bergquist, A. Stefanie Mikolaizak, Sabato Mellone, Lorenzo Chiari, Andrea B. Maier, Mirjam Pijnappels Abstract Assessment of physical performance by standard clinical tests such as the 30-sec Chair Stand (30CST) and the Timed Up and Go (TUG) may allow early detection of functional decline, even in high-functioning populations, and facilitate preventive interventions. Inertial sensors are emerging to obtain instrumented measures that can provide subtle details regarding the quality of the movement while performing such tests. We compared standard clinical with instrumented measures of physical performance in their ability to distinguish between high andRead More

Implementing behaviour change theory and techniques to increase physical activity and prevent functional decline among adults aged 61-70: The PreventIT project.

Authors:Boulton E, Hawley-Hague H, French DP, Mellone S, Zacchi A, Clemson L, Vereijken B, Todd C. Abstract The health and wellbeing benefits of engaging in physical activity (PA), and of improving strength and balance, are well documented. The World Health Organization’s recommendations of 150 min per week of moderate intensity physical activity have been adopted across the world in policy and practice recommendations. However, the number of older adults engaging in this level of PA remains low. The European Project, PreventIT, has adapted the Lifestyle-integrated Functional Exercise (LiFE) programme, which reduced falls in people 75 years and over, for a younger cohortRead More

Performance-based clinical tests of balance and muscle strength used in young seniors: a systematic literature review

  Authors: Ronny Bergquist, Michaela Weber, Michael Schwenk, Synnøve Ulseth, Jorunn L. Helbostad, Beatrix Vereijken and Kristin Taraldsen Background Many balance and strength tests exist that have been designed for older seniors, often aged ≥70 years. To guide strategies for preventing functional decline, valid and reliable tests are needed to detect early signs of functional decline in young seniors. Currently, little is known about which tests are being used in young seniors and their methodological quality. This two-step review aims to 1) identify commonly used tests of balance and strength, and 2) evaluate their measurement properties in young seniors. Methods First, a systematic literature search was conducted in MEDLINE to identify primary studies that employedRead More

Physical Activity Classification for Elderly People in Free-Living Conditions

Authors: Jonkman NH, Colpo M, Klenk J, Todd C, Hoekstra T, Del Panta V, Rapp K, van Schoor NM, Bandinelli S, Heymans MW, Mauger D, Cattelani L, Denkinger MD, Rothenbacher D, Helbostad JL, Vereijken B, Maier AB, Pijnappels M. Abstract: Physical activity is strongly linked with mental and physical health in the elderly population and accurate monitoring of activities of daily living (ADLs) can help improve quality of life and well-being. This study presents and validates an inertial sensors-based physical activity classification system developed with older adults as the target population. The dataset was collected in free-living conditions without placing constraintsRead More

Development of a clinical prediction model for the onset of functional decline in people aged 65–75 years: pooled analysis of four European cohort studies

Authors: Jonkman NH, Colpo M, Klenk J, Todd C, Hoekstra T, Del Panta V, Rapp K, van Schoor NM, Bandinelli S, Heymans MW, Mauger D, Cattelani L, Denkinger MD, Rothenbacher D, Helbostad JL, Vereijken B, Maier AB, Pijnappels M. BACKGROUND: Identifying those people at increased risk of early functional decline in activities of daily living (ADL) is essential for initiating preventive interventions. The aim of this study is to develop and validate a clinical prediction model for onset of functional decline in ADL in three years of follow-up in older people of 65-75 years old. METHODS: Four population-based cohort studies wereRead More

The Adapted Lifestyle-Integrated Functional Exercise Program for Preventing Functional Decline in Young Seniors: Development and Initial Evaluation

Authors: Schwenk M.a,b · Bergquist R.c · Boulton E.d,i · Van Ancum J.M.e · Nerz C.a · Weber M.b · Barz C.a · Jonkman N.H.e · Taraldsen K.c · Helbostad J.L.c · Vereijken B.c · Pijnappels M.e · Maier A.B.e,f · Zhang W.g · Becker C.a · Todd C.d,h,i · Clemson L.j · Hawley-Hague H.d,i Background: The Lifestyle-integrated Functional Exercise (LiFE) program is an intervention integrating balance and strength activities into daily life, effective at reducing falls in at-risk people ≥70 years. There is potential for LiFE to be adapted to young seniors in order to prevent age-related functional decline. Objective:Read More

Comparison of Standard Clinical and Instrumented Physical Performance Tests in Discriminating Functional Status of High-Functioning People Aged 61–70 Years Old

Authors:Alice Coni 1, Jeanine M. Van Ancum 2, Ronny Bergquist 3, A. Stefanie Mikolaizak 4, Sabato Mellone 1,5, Lorenzo Chiari 1,5, Andrea B. Maier 2,6and Mirjam Pijnappels 2, Abstract Assessment of physical performance by standard clinical tests such as the 30-s Chair Stand (30CST) and the Timed Up and Go (TUG) may allow early detection of functional decline, even in high-functioning populations, and facilitate preventive interventions. Inertial sensors are emerging to obtain instrumented measures that can provide subtle details regarding the quality of the movement while performing such tests. We compared standard clinical with instrumented measures of physical performance inRead More

Performance-based clinical tests of balance and muscle strength used in young seniors: a systematic literature review

Authors: Bergquist R, Weber M, Schwenk M, Ulseth S, Helbostad JL, Vereijken B, Taraldsen K Background Many balance and strength tests exist that have been designed for older seniors, often aged ≥70 years. To guide strategies for preventing functional decline, valid and reliable tests are needed to detect early signs of functional decline in young seniors. Currently, little is known about which tests are being used in young seniors and their methodological quality. This two-step review aims to 1) identify commonly used tests of balance and strength, and 2) evaluate their measurement properties in young seniors. Methods First, a systematic literatureRead More

Concurrent validity and reliability of the Community Balance and Mobility scale in young-older adults

  Authors, Michaela Weber, Jeanine Van Ancum, Ronny Bergquist, Kristin Taraldsen, Katharina Gordt, A. Stefanie Mikolaizak, Corinna Nerz, Mirjam Pijnappels, Nini H. Jonkman, Andrea B. Maier, Jorunn L. Helbostad, Beatrix Vereijken, Clemens Becker and Michael Schwenk Background With the growing number of young-older adults (baby-boomers), there is an increasing demand for assessment tools specific for this population, which are able to detect subtle balance and mobility deficits. Various balance and mobility tests already exist, but suffer from ceiling effects in higher functioning older adults. A reliable and valid challenging balance and mobility test is critical to determine a young-older adult’s balance and mobility performance and to timely initiate preventive interventions. The aim was to evaluate the concurrent validity, inter- and intrarater reliability, internal consistency, and ceiling effects of a challengingRead More

Complexity of Daily Physical Activity Is More Sensitive Than Conventional Metrics to Assess Functional Change in Younger Older Adults

Authors: Wei Zhang 1,* , Michael Schwenk 2,3, Sabato Mellone 4, Anisoara Paraschiv-Ionescu 1, Beatrix Vereijken 5 , Mirjam Pijnappels 6, A. Stefanie Mikolaizak 2, Elisabeth Boulton 7, Nini H. Jonkman 6 , Andrea B. Maier 6,8, Jochen Klenk 2,9, Jorunn Helbostad 5, Kristin Taraldsen 5and Kamiar Aminian 1 Abstract The emerging mHealth applications, incorporating wearable sensors, enables continuous monitoring of physical activity (PA). This study aimed at analyzing the relevance of a multivariate complexity metric in assessment of functional change in younger older adults. Thirty individuals (60–70 years old) participated in a 4-week home-based exercise intervention. The Community Balance and Mobility ScaleRead More

German version of the Community Balance and Mobility Scale : Translation and evaluation of measurement properties.

Authors: Gordt K1, Mikolaizak AS2, Nerz C2, Barz C2, Gerhardy T1, Weber M1, Becker C2, Schwenk M3,4,5. Abstract BACKGROUND: Tools to detect subtle balance deficits in high-functioning community-dwelling older adults are lacking. The Community Balance and Mobility Scale (CBM) is a valuable tool to measure balance deficits in this group; however, it is not yet available in the German language. OBJECTIVE: The aim was 1) to translate and cross-culturally adapt the CBM into the German language and 2) to investigate the measurement properties of the German CBM (G-CBM). MATERIAL AND METHODS: The original CBM was translated into the German language according to establishedRead More

Interview with Andrea Maier in ICT&Health (in Dutch) ‘Gezonder ouder worden met een app’

“We worden steeds ouder maar ziektes die voorheen vooral op hoge leeftijd voorkwamen, zien we nu op steeds jongere leeftijd optreden. Gemiddeld hebben vrouwen al op hun 41ste en mannen op hun 45ste een chronische ziekte”, zegt verouderingsonderzoeker en hoogleraar interne geneeskunde Andrea Maier. In haar onderzoek naar de invloed van leefstijl op de zelfredzaamheid van ouderen ontdekte ze goede mogelijkheden om ook op jongere leeftijd actief bezig te zijn met gezonder ouder worden. De smartphone speelt daarbij een belangrijke rol. “Als je via een app ziet welke gezondheidsrisico’s je loopt, kun je daar je gedrag op aanpassen.” “De smartphoneRead More

Evidence and theory-based interventions to support healthy ageing

Dr Lis Boulton moved into behaviour change research following a successful career in management in the    health and social care sector, working for local government and various charities as both a service provider and commissioner. Her PhD considered the involvement of older adults in designing and implementing interventions to promote physical activity. Lis currently works on the EC PreventIT project, designing and evaluating an App- based behavioural intervention. Lis has a particular interest in the translation of evidence into practice. She is Chair of the Board of a large local charity, Age UK Calderdale & Kirklees, and is aRead More

Concern about Falling and Complexity of Free-Living Physical Activity Patterns in Well-Functioning Older Adults.

Abstract BACKGROUND: Fall-related psychological concerns are common among older adults, potentially contributing to functional decline as well as to restriction of activities and social participation. To effectively prevent such negative consequences, it is important to understand how even very low concern about falling could affect physical activity behavior in everyday life. We hypothesized that concern about falling is associated with a reduction in diversity, dynamics, and performance of daily activities, and that these features can be comprehensively quantified in terms of complexity of physical activity patterns. METHODS: A sample of 40 community-dwelling older adults were assessed for concern about fallingRead More

Feasibility and Effectiveness of Intervention Programmes Integrating Functional Exercise into Daily Life of Older Adults: A Systematic Review

 Full paper : LiFE – Review As published in Gerontology September 15, 2017. This systematic review provides a comprehensive overview of the available evidence concerning integrated functional exercise training in older adults. Some studies reported advantages of this training concept compared to structured exercise training, including higher adherence, increased effectiveness for improving selected motor per- formances, and simultaneously increasing PA andReducing falls. However, the number of RCTs was low, and studies used different training concepts hampering their comparability. NRS provided some evidence about the effectiveness of the behavioural change concept and the feasibility of integrated training in impaired target popu- lations. MoreRead More

Mobile Health Applications to Promote Active and Healthy Ageing

Full paper: sensors-17-00622-v2 Abstract: The European population is ageing, and there is a need for health solutions that keep older adults independent longer. With increasing access to mobile technology, such as smartphones and smartwatches, the development and use of mobile health applications is rapidly growing. To meet the societal challenge of changing demography, mobile health solutions are warranted that support older adults to stay healthy and active and that can prevent or delay functional decline. This paper reviews the literature on mobile technology, in particular wearable technology, such as smartphones, smartwatches, and wristbands, presenting new ideas on how this technology canRead More

White Paper of the Project Results in PreventIT (Deliverable 8.2)

Full paper: D8.2.White paper of project results first release.v1.0 This deliverable reports on the results that have been obtained so far, half-way through the PreventIT project, in the form of a white paper that covers the development of i) the content and behavioural change strategy of the lifestyle-integrated intervention, ii) tools for risk screening and profiling, iii) the back-end and front-end technology of the mHealth system under development in PreventIT, the so-called iPAS, and iv) intervention outcomes regarding functional performance and behavioural complexity. It also reports on two pilot studies that tested the two intervention arms on a sample from theRead More